Lady Gaga and Ariana Grande's collaboration "Rain on Me" debuted at No. 1 on the Billboard Hot 100, making chart history in several ways.

It's the first time that a song by multiple female solo artists has been replaced at No. 1 by another song by multiple female solo artists.

"Rain on Me" replaces the remix of "Savage," by Megan Thee Stallion and Beyoncé.

It also marks Grande's fourth song to debut at No. 1 on the chart – more than any other artist in history. Mariah Carey, Drake and Justin Bieber each have three.

It is Gaga's fifth chart-topper overall, and her second No. 1 debut. She's now set the record for the longest span between No. 1 debuts: It's been nine years, three months and a week since "Born This Way" topped the chart in 2011.

Gaga is now the third artist to have reached No. 1 on the Billboard Hot 100 in the 2000s, 2010s and 2020s, following Mariah Carey and Beyoncé.

"Rain on Me" is the second single from Gaga's new album Chromatica, released Friday.